Radiomimetic Model
نویسنده
چکیده
Direct selection for 12 mutations (blm) conferring hypersensitivities to lethal effects of bleomycins in Saccharomyces cerevisiae resulted in mutants exhibiting cross-hypersensitivity to ionizing radiation and hydrogen peroxide. Remaining mutations did not confer cross-hypersensitivity to radiation. All blm mutations were recessive, except codominant blm3-1, and were assigned to seven complementation groups.
منابع مشابه
Resistance and Cross Resistance of Escherichia Coli S Mutants to the Radiomimetic Agent Nitrofurazone.
Woody-Karrer, Pearl (Palo Alto Medical Research Foundation, Palo Alto, Calif.) and Joseph Greenberg. Resistance and cross resistance of Escherichia coli S mutants to the radiomimetic agent nitrofurazone. J. Bacteriol. 85:1208-1216. 1963.-Cross-resistance relationships are described for 73 mutants of Escherichia coli strain S selected in one step for resistance to nitrofurazone. The test agents ...
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متن کاملRadiomimetic properties of 2-amnipurine in Escherichia coli.
Zampieri, Antonio (Palo Alto Medical Research Foundation, Palo Alto, Calif.), and Joseph Greenberg. Radiomimetic properties of 2-aminopurine in Escherichia coli. J. Bacteriol. 91:1773-1774. 1966.-A radioresistant mutant (R(4)) of Escherichia coli strain S was found to be resistant to 2-aminopurine. The composition of the post-treatment plating medium and temperature of incubation did not influe...
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Cupferron, the ammonium salt of N-nitro-sophenylhydroxylamine, enhances the frequencies of structural chromosome changes produced by x-rays in the root tips of the broad bean, Vicia faba (7, 4-6). The enhancement produced at low oxygen pressures (0.3 to 5 per cent 02 in the gas phase) is particularly striking and appears to be a result of the inhibitory action of cupferron on oxygen consumption...
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Curry, Janet (Stanford Research Institute, Menlo Park, Calif.) and Joseph Greenberg. Filament formation in radioresistant mutants of Escherichia coli S after treatment with ultraviolet light and radiomimetic agents. J. Bacteriol. 83:38-42. 1962.-The effect of ultraviolet light and of five radiomimetic compounds on cell division, growth in liquid medium, and growth in solid medium of Escherichia...
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تاریخ انتشار 2003